NAME Analysis and modulation of biomarkers by means of targeted active compounds
This asset includes a set of proprietary technologies for the establishment of nutritional strategies adapted to the needs of the population based on genetic and microbiome studies. We identify biomarkers that, through targeted active compounds, can be modulated to achieve the prevention of chronic diseases. • Genetic and microbiome diagnosis to establish the nutritional needs of different population cohorts. • Digital platform aimed at the correlation between targeted active compounds and the modulation of biomarkers associated with the health status.
FIELDS OF APPLICATION
Digital health
In-Vitro diagnostics
MOST OUTSTANDING EQUIPMENT AND COMPONENTS
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Bioinformatic analysis software
Bioinformatic analysis software and equipment from Life Technologies (QuantStudio Real Time PCR software v1.1) for analysis and interpretation of sequencing results
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DNA ultra-sequencer
Illumina Miseq DNA Ultra-Sequencer for High Throughput and High Capacity DNA Sequencing (Latest Generation)
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Liquid chromatography equipment
Liquid chromatography equipment coupled with high-resolution mass spectrometry and ionic mobility, from Bruker Española S.A. (TIMSTOF)
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Minibio 500M bioreactor
Minibio 500M bioreactor (4 mini reactors) from GETINGA (Applikon-My Control). Reactor with stirring and temperature control for selection of enzymes and establishment of enzymatic reactions
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Sorvall BIOS16 centrifuge
Sorvall BIOS16 centrifuge, from Thermo Fischer Scientific, enables high-quality bioprocessing methods of collection, separation, and purification that require reproducibility and traceability between runs
SERVICES OFFERED BY THE ASSET
Formulation of ingredients
Formulation of ingredients and design of intake guidelines adapted to personal needs.
Genome study
Study and analysis of the genome in biological samples. Identification of biomarkers related to the health status and allowoing their modulation through targeted active compounds
Identification of targeted active compounds
Identification of differential active compounds with a proven effect to achieve a personalized and optimal state of health. Bioinformatics tools for digitizing genome and microbiome data and for statistical analysis that allow the use of the results generated in combination with a database of active compounds, establishing correlations between targeted active compounds and the modulation of biomarkers associated with health status
Microbiome study
Characterization of the microbial species present in different biological matrices (intestinal, oral, dermal), allowing to predict the predisposition of the person to the development of certain diseases, as well as to characterize the senescence process of the individual (healthy aging).
Precision nutrition
Data analytics to establish nutritional guidelines and perform a dynamic management of personalized diets
ENTITY MANAGING THE ASSET
Contact person:
Mari-Carmen Villaran Velasco
mcarmen.villaran@tecnalia.com