NAME Birika bidez emateko formulazioak diseinatzeko, optimizatzeko eta karakterizatzeko laborategia.

MOST OUTSTANDING EQUIPMENT AND COMPONENTS

• Alberta Gorge (Copley brand)

  Alberta Gorge (Copley brand):
  Designed to improve in vivo / in vitro correlation (IVIVC) during inhaled product testing. It more accurately reflects deposition behavior in the human throat, thus improving the relevance of test data in an R&D environment.

• Breathing Simulator (Copley brand):

  Breathing Simulator (Copley brand): Biopharmaceutical characterisation equipment for pulmonary formulations. Generates user-defined and patient-derived breathing profiles that more closely mimic real-world clinical situations.
  Technical Features:
  -Tests nebulisers and metered dose inhalers (MDI) with spacers/valved holding chambers (VHC).
  - Has a maximum volume of 900 mL, making it ideal for the low volume tidal breathing applications required in these chapters.
  -It offers higher volumes (500 mL up to 5000 mL) and the higher power (maximum flow rate of 240 L/min) needed to generate the typical profiles of patients using MDI and dry powder inhalers (DPI) under forced inhalation conditions.

• NGI Cascade Impactor (Copley brand)

  NGI Cascade Impactor (Copley brand): Equipment for determining the aerodynamic particle size distribution (APSD) of orally inhaled pharmaceutical products (OIDP). It is used to test all inhalation formulations and devices: MDI, DPI, nebulisers and nasal sprays and aerosols.

• Spray-dryer B-290 (Buchi brand)

  Spray-dryer B-290 (Buchi brand): Equipment used for particle size modification, suspension drying, particle coating, microcapsule and microparticle manufacturing, peptide, protein and antibody stability enhancement, controlled release and flavour masking.

• Spraytec (brand : Malvern)

  Spraytec (brand : Malvern) : A laser diffraction system that allows the measurement of particle and droplet size distributions of aerosols, in real time, for a more efficient development of aerosol products.
  Technical features:
  -Measure across a wide size range (0.1 - 2000 microns) without requiring constant optical changes.
  -Resolve rapid changes in droplet size over time, measuring up to 10,000 measurements per second.
  - Provide accurate, concentration-independent results using patented multiple scattering analysis.
  - Characterise broad spray plumes without risking optical contamination.
  -Size history analysis software.